What I Am All About

Wednesday, December 25, 2019

My Quora Answer to "Parents, what did your doctor do that ticked you off?"

After delivery and while she was still sedated (it was a C-section), and while I was in the nursery with my new pride and joy, a nurse or other staff person convinced my wife to sign the consent forms. And they KNEW of our stance beforehand! They mutilated our baby against our wishes. And the insurance company paid them for it!

http://bit.ly/2MThQ8U

Comments
Phoenix Andrews: Slightly off topic but I’m curious as to why you wouldn’t want to circumcise your son. I’m not a mom nor do I have a penis so I personal don’t have an experience with it in that sense. From what I know it’s better for your hygiene not to have it. Not judging you I’m just curious.

My Reply

Tuesday, September 24, 2019

Life Extension and Brain Boosters

The following is a cut-and-paste response with my added comments and advice to a real friend of mine who has cognitive issues. No matter what station in life you are at, there are many take home issues here. As always, consult with your physician before blahdy blahdy Hell.

Brain Boosters
Josh: this is mostlly from the Life Extension website. I've emboldened the really important things you need to know and put my thoughts in italics. While it addresses cognitive decline with aging, It's great advice for all of us. At the end I'll give my best recommendation for you.

Proactive lifestyle changes, cognitive training, and nutritional interventions such as phosphatidylserine and glyceryl phosphoryl choline have been shown to decrease the rate of intellectual decay and potentially reverse age-related cognitive decline.

Several dietary and lifestyle changes can help reduce age-related cognitive decline:

  1. Switch from a western diet high in simple sugars and saturated fats to a Mediterranean diet high in mono- and polyunsaturated omega-3 fats, fiber, and polyphenol.
  2. Caloric restriction may improve learning and memory
  3. Cognitive stimulation and training, including playing chess and speaking more than one language, can enhance cognitive reserve and convey protection against loss of brain function
  4. Exercise is known to increase levels of brain-derived neurotrophic factor, which can lead to enhanced cognitive function. Tomatoes also contain a Nerve Growth-like Factor which is better absorbed with fats like Olive and coconut oils.
  5. Moderate alcohol consumption (up to 2 drinks/day) and caffeinated coffee consumption (~3 cups/day) may convey protection against cognitive decline. Dry red wines!
  6. Fish Oil: Daily omega-3 supplementation was independently associated with a dramatic reduction in cognitive decline over a 1.5-year period in an aging study population.
  7. Phosphatidylserine: Human clinical trials have found that supplementing with phosphatidylserine improves cognitive function in aging subjects with cognitive impairment.
  8. Glyceryl Phosphoryl Choline (GPC): Patients taking GPC showed neurological improvement and relief of clinical symptoms of chronic cerebral deterioration that was superior or equivalent to that obtained with prescription drugs.
  9. Acetyl-L-carnitine: A meta-analysis of data from over 21 studies shows that supplementation with acetyl-L-carnitine improves cognitive deficits observed during aging and pathological brain deterioration. I recommend a combination supplement of ALC & ALA (alpha lipoic acid). Here's why: http://bit.ly/2lcZW4w

  1. Huperzine A: Patients with Alzheimer’s disease improved their scores on standard cognitive tests after supplementing with huperzine A.

Several other medications with potential brain-protective effects are:

  1. Piracetam (Nootropil) and levetiracetam (Keppra) are anti-seizure medications sometimes used as cognitive enhancers. These and several related drugs (the “racetams”) are often colloquially referred to as “nootropics.” Preclinical evidence suggests these medications may reduce neuroinflammation, improve mitochondrial function, and prevent β-amyloid-induced neuronal dysfunction. IIn early research, levetiracetam was found to improve cognitive performance on a memory test.Findings from a clinical trial in cognitive impairment and dementia patients suggest piracetam may be most effective in those with depressive symptoms. Whether these medications hold benefits for patients with age-related cognitive decline and mild cognitive impairment has not yet been established. Also, the regulatory status of piracetam and related compounds is vague, and legal status varies between countries.
  2. Zileuton (Zyflo) is an inhibitor of the pro-inflammatory enzyme 5-lipoxygenase. While its main use is as an anti-asthma medication, zileuton has demonstrated some intriguing effects on brain function in preclinical trials. In animal research, zileuton has been found to reduce brain levels of β-amyloid and tau, as well as amyloid- and tau-related neuroinflammation, neuronal dysfunction, and cognitive impairment. Other animal research suggests zileuton may reduce brain damage and cognitive losses after stroke. The possible usefulness of zileuton in age-related cognitive decline, mild cognitive impairment, and dementia awaits future investigation.
  3. Hydergine (co-dergocrine mesylate), a mixture of ergot alkaloids, has been found to improve cognitive function and mood in preliminary trials in elderly subjects with age-related cognitive dysfunction.Its mechanism of action is not completely understood; however, it appears to modulate neurotransmitter activity, improve cerebral metabolism, and increase antioxidant enzyme activity in the brain. Despite interesting findings, there have been no clinical trials investigating hydergine’s usefulness in age-related cognitive decline and mild cognitive impairment for decades.
  4. Selegiline (Deprenyl) is a monoamine oxidase-B inhibitor that blocks the enzymatic breakdown of certain neurotransmitters, such as dopamine and serotonin. It is used to treat Parkinson disease, Alzheimer disease, and major depressive disorder, and is thought to have anti-aging effects. Selegiline was found to improve cognitive performance in a six-month preliminary trial in human subjects with mild-to-moderate brain atrophy. Studies in animals suggest it can reduce oxidative stress, protect against brain damage due to loss of blood flow, and preserve neurotransmission and memory. More clinical trials are needed to ascertain the potential benefits of this medication in age-related cognitive decline.
  5. Centrophenoxine or meclofenoxate (Lucidril) enhances activation of cholinergic pathways in the central nervous system. An early trial in elderly subjects found centrophenoxine improved formation of new memory and increased subjective reports of mental alertness.Animal research has found that this medication may protect against cognitive losses due to aluminum toxicity, drug toxicity,and lack of blood flow.
My basic prescription medication support list is: Hydergine, Piracetam, and Deprenyl. Ask your doc. While Hydergine and Deprenyl are available by prescription in the US, you need to order Piracetam offshore.. 
Diet
An eating pattern based on the traditional Mediterranean diet has been shown to have anti-aging effects on brain, cardiovascular, and metabolic functions, and on overall longevity. Findings from a variety of studies suggest eating a Mediterranean-style diet can slow cognitive decline and may reduce risk of dementia. If you are already eating Indian cuisine, it will be easy to go.
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Mediterranean. I asked about fava beans because they increase dopamine levels in your brain. If you're using them as medicine, shoot for either breakfast or lunch since they can cause insomnia.

Mediterranean diet. With its emphasis on fruits, vegetables, unrefined whole grains, legumes, and extra virgin olive oil, as well as moderate amounts of seafood, fermented dairy products, and red wine with meals,200 the traditional Mediterranean diet provides ample amounts of critical nutrients such as mono- and polyunsaturated fatty acids, antioxidants, vitamins, minerals, and phytonutrients. It can be used as a template that can be adapted to favor local and seasonal availability of specific foods.

A study including 832 participants examined every two to three years for up to 18 years found that those whose diets most closely reflected a Mediterranean diet experienced significantly less cognitive decline than those whose diets least reflected a Mediterranean diet. A study based on data collected over 16 years from men participating in the Health Professionals’ Follow-up Study found that those whose diets were most Mediterranean-like were 36% less likely to report poor subjective cognitive function than those whose diets were least Mediterranean-like.Examining the brains of cognitively normal older-age subjects has revealed that adherence to a Mediterranean-like dietary pattern is associated with reduced β-amyloid accumulation. The components of the diet most closely linked to this effect were high fruit and vegetable consumption and moderate wine consumption.

1. Olive oil😉

Use extra virgin olive oil on vegetables, legumes, salads, stir-fries, and sautés;

Flavor food with herbs, spices, garlic, onion, and lemon

2. Vegetables

Mainly starchy vegetables
Have vegetables with both lunch and dinner;

Use vegetables as a main dish often;

Have some raw, dressed with olive oil and vinegar, every day

3. Fruits

Fruit products often contain added sugar

(Low consumption)

Eat raw fruits as dessert most days;

Include a variety of seasonally appropriate fruits

4. Unrefined whole grains
Use whole grain bread, pasta, and flour;

Include whole unrefined grains often

5. Legumes

Include a variety of beans, lentils, and peas;

Cook dried beans or choose canned beans without additives.

6. Nuts and olives
Have nuts and olives as snacks;

Eat a handful of raw nuts daily;

Choose a variety of nuts

7. Moderate seafood intake

Fatty fish (tuna, salmon, sardines) twice or more weekly;

Shellfish (oysters, clams, squid, shrimp) occasionally

8. Moderate fermented dairy (yogurt and cheese)
Use unsweetened yogurt and flavor with fruit;

Have small amounts of fresh or cured cheese occasionally;

Avoid ice cream

9. Home cooking
  1. Limited intake of homemade baked goods and processed baked goods (high in sugar, processed fats, and additives). 8n fact Josh, just avoid altogether.
  2. Bake at home;
  3. Use olive oil instead of butter;
Ghee is good, though. So are coconut oil and MCT oil. Read up on Bulletproof Coffee which is coffee with ghee (or range-fed organic butter such as KerryGold). www.bulletproofcoffee.com I think. It's what I drink.
  1. Eat baked goods only occasionally or better, not at all 
  2. Little meat and limited poultry. I disagree with this. Range-fed pork and chicken, wild salmon and tuna, crab and shrimp, calamari, and lobster are tasty and healthy foods. Avoid clams and other shellfish since they are filter-feeders which means you are eating fish poop and spawn.

High intake of red and processed meats:
  1. Large portions. Limit meat consumption to a fistful per meal.
  2. Choose lean poultry. Free-range only.

Red wine/Beverages
  1. Avoid beer, hard liquor, and sugar-sweetened soft drinks.
  2. Include moderate amounts (up to 1 glass per day for women and 2 glasses per day for men) of wine, preferably red, always with meals. Merlot, Shiraz, and Port. You want a red wine so dry it makes you pucker. 
  3. Drink water instead of soft drinks. Limit fruit juices most of all. If you decide to do Intermittent Fasting, break your fast with a single glass of apple or grape juice. These replenish your liver's glycogen stores but too much decreases sperm count and semen volume.

Caloric Restriction
Caloric restriction, a dietary intervention in which calorie intake is reduced but adequate nutrient intake is preserved, has been shown to delay the onset of age-related diseases and extend lifespan in many organisms.216 This effect is thought to be due to a triggering of resilience mechanisms that enhance cellular resistance to stress. This effect is known as hormesis.

In rodent models, caloric restriction was associated with decreased neural stem cell senescence, increased neuroplasticity, and better cognitive performance.

Specifically, caloric restriction has been found in animal models to stimulate neural stem cell activity and promote normal metabolism of phospholipids needed for myelin production, lower stress reactivity and stress-related changes in brain structure, and induce epigenetic changes that support youthful gene expression in aging brains. Some of the same metabolic and molecular changes and health benefits associated with caloric restriction in animals have been demonstrated in humans engaging in 25% caloric restriction or through an intermittent fasting strategy, combined with physical activity.

I recommend Intermittent Fasting. A good strategy is by Brad Pillon at "Eat. Stop. Eat:" http://bit.ly/2kHDJLL

So my best advice for you:
  1. Medications: Piracetam, Hydergine, and Deprenyl
  2. Supplements: ALA!ALC, Phosphatidylserine, fish oil, and glyceryl phosphoryl choline
  3. Food: Mediterranean diet but with more range-fed meats, fava beans, eat low on the Glycemic Index
  4. Drinks: water, dry red wines, Bulletproof Coffee.

Tuesday, August 27, 2019

Kidnapping, Murican, embassy, Nicaragua, Ben

My Letter to the Newest Ambassador at the American Embassy in Nicaragua

Please forward to Ambassador Kevin K. Sullivan

I just read about your appointment almost a year ago, so here's a belated congratulations. I never received a response from your predecessor, so I hope I can get some satisfaction from you. 

She may or may not have told you about me, but over the 2013 Thanksgiving holiday, I left my then 12-year old son Ben with some "friends" from Casa Ben Linder while I went to get some cough syrup from a nearby pulperia. Instead of picking me up there as we discussed, they went instead to a supermercado much further away. After waiting for them an extra half hour, I went back to where the Thanksgiving party had been, but it was closed up.

In looking for Ben, I was mugged first by a hang of putas who stole my wallet and phone. The next night I was mugged 3 times on my way to the embassy, the last time left for dead.

While I was desperately seeking my son, the CBL people arranged with agent James Bjorkman at the embassy and my then-wife Angie to kidnap Ben away from me, spread lies about me across the Nicaraguan agencies like Mi Familia, and deliberately keep me in the dark about Ben's whereabouts and status. Bjorkman then flew Angie to Managua and then both her and my son back to the states while your agent made sure I was out of the way by getting the police to stick me in an immigration detention center for 5 days.

Basically, I  never wanted anything to do with the embassy again, but after a month of homelessness and hunger in Léon, I gave up, packed my tail between my legs, and went back there. Under EXTREME mental duress, I signed a form saying I would pay back the return flight costs to the State Department. Strange thing about the cost, too. I flew a family of 5 from Miami to Managua for $1000. Yet my single flight back cost what? I think close to $1500. Just one more kick in the nuts from the embassy you inherited.

Because of the muggings, I am disabled and on a fixed Social Security Disability Income. I cannot afford to pay the extortion money to get my passport back. I want to eventually go back to Nicaragua and continue where I left off: healing and teaching those wonderful people. Despite the muggers. Thanks,

Michael Mangold, M.D.

https://amzn.to/2GS2REy

http://bit.ly/2HvNjtn

Monday, April 29, 2019

THE LIES CONTINUE

I lived with a pathological liar for 14 years. In the Summer of Lies (2012), I discovered the hard way how destructive this can be. Angie started the feast by covering the fact that she had been making out with a woman named Christa while keeping me and the kids waiting in the car. She lied through our divorce and the judge never called her on it, despite my protestations. But the biggest lie is still destroying my integrity and friendships.

My daughter Ami has blessed me with a wonderful grandson, Max. I have been impoverished until recently since I was abandoned in Nicaragua by Angie when she conspired with the American embassy there to kidnap my son Ben. This is how it ties in with this blog. Anyway, I feel guilty about not being a generous Grandfather to all three grandsons of mine. It bothers the hell out of me, so I offered Ami a proposal: I would adopt Max, who would then be the recipient of my Social Security Disability Insurance payments after I die. As it now stands, Angie is, just by virtue of having been married to me. Think about that: I became disabled because of the muggings I endured in Managua looking for Ben; she ruined my family, my finances, and my career, and yet our guvment believes she should benefit by death. I seriously am surprised she hasn't put a hit on me.

So when Ami told Chris about my offer, he sent me a nasty message telling me what an awful person I am. At the end, to "get back" at me, he mentioned the rumor, the terrible lie, Angie has been spreading since the Summer of Lies: that I "touched our daughter Savannah like a man touches his wife." Thinking about it makes me physically sick, so here is my response, two weeks in the making:


Read it and weep. I do.